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pentobarbital will reduce the extent or impact of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.pentobarbital will lessen the extent or influence of alosetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unfamiliar.benzhydrocodone/acetaminophen and pentobarbita